{"id":14980,"date":"2025-06-25T22:00:00","date_gmt":"2025-06-25T22:00:00","guid":{"rendered":"https:\/\/modernsciences.org\/staging\/4414\/?p=14980"},"modified":"2025-06-13T16:51:40","modified_gmt":"2025-06-13T16:51:40","slug":"black-mould-health-risks-toxicology-myths-indoor-air-quality-mycotoxins-june-2025","status":"publish","type":"post","link":"https:\/\/modernsciences.org\/staging\/4414\/black-mould-health-risks-toxicology-myths-indoor-air-quality-mycotoxins-june-2025\/","title":{"rendered":"Is black mould really as bad for us as we think? A toxicologist explains"},"content":{"rendered":"\n\n\n<div class=\"theconversation-article-body\">\n    <figure>\n      <img  decoding=\"async\"  src=\"data:image\/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABAQMAAAAl21bKAAAAA1BMVEUAAP+KeNJXAAAAAXRSTlMAQObYZgAAAAlwSFlzAAAOxAAADsQBlSsOGwAAAApJREFUCNdjYAAAAAIAAeIhvDMAAAAASUVORK5CYII=\"  class=\" pk-lazyload\"  data-pk-sizes=\"auto\"  data-pk-src=\"https:\/\/images.theconversation.com\/files\/672356\/original\/file-20250604-56-c69m76.jpg?ixlib=rb-4.1.0&#038;rect=0%2C0%2C1000%2C562&#038;q=45&#038;auto=format&#038;w=754&#038;fit=clip\" >\n        <figcaption>\n          \n          <span class=\"attribution\"><a class=\"source\" href=\"https:\/\/www.shutterstock.com\/image-photo\/spot-mold-mould-mildew-fungus-on-2462902895\" target=\"_blank\" rel=\"noopener\"> Peeradontax\/Shutterstock<\/a><\/span>\n        <\/figcaption>\n    <\/figure>\n\n  <span><a href=\"https:\/\/theconversation.com\/profiles\/ian-musgrave-1808\" target=\"_blank\" rel=\"noopener\">Ian Musgrave<\/a>, <em><a href=\"https:\/\/theconversation.com\/institutions\/university-of-adelaide-1119\" target=\"_blank\" rel=\"noopener\">University of Adelaide<\/a><\/em><\/span>\n\n  <p>Mould in houses is unsightly and may cause unpleasant odours. More important though, mould has been linked to a range of health effects \u2013 especially <a href=\"https:\/\/theconversation.com\/sudden-mould-outbreak-after-all-this-rain-youre-not-alone-but-you-are-at-risk-177820\" target=\"_blank\" rel=\"noopener\">triggering asthma<\/a>.<\/p>\n\n<p>However, is mould exposure linked to a serious lung disease in children, unrelated to asthma? As we\u2019ll see, <a href=\"https:\/\/www.smh.com.au\/national\/how-bad-science-warped-our-ideas-about-black-mould-20250602-p5m45l.html\" target=\"_blank\" rel=\"noopener\">this link may not be real<\/a>, or if it is, it\u2019s so rare to not be a meaningful risk. Yet we still hear mould in damp homes described as \u201ctoxic\u201d.<\/p>\n\n<p>Indeed, mouldy homes can harm people\u2019s health, but not necessarily how you might think.<\/p>\n\n<h2 id=\"what-is-mould\">What is mould?<\/h2>\n\n<p><a href=\"https:\/\/www.health.nsw.gov.au\/environment\/factsheets\/Pages\/mould.aspx\" target=\"_blank\" rel=\"noopener\">Mould<\/a> is the general term for a variety of fungi. The mould that people have focused on in damp homes is \u201cblack mould\u201d. This forms unsightly black patches on walls and other parts of damp-affected buildings. <\/p>\n\n<p>Black mould is not a single fungus. But when people talk about black mould, they generally mean the fungus <em><a href=\"https:\/\/www.cdc.gov\/mold-health\/data-research\/facts-stats\/index.html\" target=\"_blank\" rel=\"noopener\">Stachybotrys chartarum<\/a><\/em> or <em>S. chartarum<\/em> for short. It\u2019s one of experts\u2019 <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s13225-018-0413-9\" target=\"_blank\" rel=\"noopener\">top ten feared fungi<\/a>.<\/p>\n\n<p>The focus on this species comes from a <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1566217\/\" target=\"_blank\" rel=\"noopener\">report in the 1990s<\/a> on cases of haemorrhagic lung disease in a number of infants. This is a rare disease where blood leaks into the lungs, and can be fatal. The report suggested chemicals known as mycotoxins associated with this species of fungus were responsible for the outbreak.<\/p>\n\n<h2 id=\"what-are-mycotoxins\">What are mycotoxins?<\/h2>\n\n<p>A variety of fungi produce <a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/mycotoxins#:%7E:text=Mycotoxins%20are%20toxic%20compounds%20that,dried%20fruits%2C%20nuts%20and%20spices.\" target=\"_blank\" rel=\"noopener\">mycotoxins<\/a> to <a href=\"https:\/\/apsjournals.apsnet.org\/doi\/10.1094\/PHYTO-02-22-0053-SYM\" target=\"_blank\" rel=\"noopener\">defend themselves<\/a>, among other reasons. <\/p>\n\n<p>Hundreds of different chemicals are listed as myocytoxins. These include ones in <a href=\"https:\/\/theconversation.com\/its-wild-mushroom-season-in-australia-heres-how-to-stay-safe-and-avoid-poisoning-256561\" target=\"_blank\" rel=\"noopener\">poisonous mushrooms<\/a>, and ones associated with the soil fungi <em>Aspergillus flavus<\/em> and <em>A. parasiticus<\/em>.<\/p>\n\n<p>The fungus typically associated with black mould <em>S. chartarum<\/em> can produce <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC145304\/\" target=\"_blank\" rel=\"noopener\">several mycotoxins<\/a>. These include <a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Roridin-A#section=Hazard-Classes-and-Categories\" target=\"_blank\" rel=\"noopener\">roridin<\/a>, which inhibits protein synthesis in humans and animals, and <a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/137628465#section=Toxicity\" target=\"_blank\" rel=\"noopener\">satratoxins<\/a>, which have numerous toxic effects including bleeding in the lungs. <\/p>\n\n<p>While the satratoxins, in particular, were mentioned in the <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1566217\/\" target=\"_blank\" rel=\"noopener\">report from the 90s<\/a> in children, there are <a href=\"https:\/\/www.cdc.gov\/mmwr\/preview\/mmwrhtml\/mm4909a3.htm\" target=\"_blank\" rel=\"noopener\">some problems<\/a> when we look at the evidence.<\/p>\n\n<p>The amount of mycotoxins <em>S. chartarum<\/em> makes <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC145304\/\" target=\"_blank\" rel=\"noopener\">can vary considerably<\/a>. Even if significant amounts of mycotoxin are present, getting them into the body in the required amount to cause damage is another thing.<\/p>\n\n<p>Inhaling spores in contaminated (mouldy) homes is the most probable way mycotoxins enter the body. For instance, we know mycotoxins can be found in <em>S. chartarum<\/em> <a href=\"https:\/\/www.mdpi.com\/2072-6651\/14\/8\/515\" target=\"_blank\" rel=\"noopener\">spores<\/a>. We also know direct injection of high concentrations of mycotoxin-bearing spores <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9038239\/\" target=\"_blank\" rel=\"noopener\">directly in the noses of mice<\/a> can cause some lung bleeding.<\/p>\n\n<figure class=\"align-center zoomable\">\n            <a href=\"https:\/\/images.theconversation.com\/files\/672436\/original\/file-20250605-56-ozx34.jpg?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=1000&amp;fit=clip\" target=\"_blank\" rel=\"noopener\"><img  decoding=\"async\"  alt=\"Stachybotrys chartarum mould\"  src=\"data:image\/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABAQMAAAAl21bKAAAAA1BMVEUAAP+KeNJXAAAAAXRSTlMAQObYZgAAAAlwSFlzAAAOxAAADsQBlSsOGwAAAApJREFUCNdjYAAAAAIAAeIhvDMAAAAASUVORK5CYII=\"  class=\" pk-lazyload\"  data-pk-sizes=\"auto\"  data-ls-sizes=\"(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px\"  data-pk-src=\"https:\/\/images.theconversation.com\/files\/672436\/original\/file-20250605-56-ozx34.jpg?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip\"  data-pk-srcset=\"https:\/\/images.theconversation.com\/files\/672436\/original\/file-20250605-56-ozx34.jpg?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=600&amp;h=400&amp;fit=crop&amp;dpr=1 600w, https:\/\/images.theconversation.com\/files\/672436\/original\/file-20250605-56-ozx34.jpg?ixlib=rb-4.1.0&amp;q=30&amp;auto=format&amp;w=600&amp;h=400&amp;fit=crop&amp;dpr=2 1200w, https:\/\/images.theconversation.com\/files\/672436\/original\/file-20250605-56-ozx34.jpg?ixlib=rb-4.1.0&amp;q=15&amp;auto=format&amp;w=600&amp;h=400&amp;fit=crop&amp;dpr=3 1800w, https:\/\/images.theconversation.com\/files\/672436\/original\/file-20250605-56-ozx34.jpg?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;h=503&amp;fit=crop&amp;dpr=1 754w, https:\/\/images.theconversation.com\/files\/672436\/original\/file-20250605-56-ozx34.jpg?ixlib=rb-4.1.0&amp;q=30&amp;auto=format&amp;w=754&amp;h=503&amp;fit=crop&amp;dpr=2 1508w, https:\/\/images.theconversation.com\/files\/672436\/original\/file-20250605-56-ozx34.jpg?ixlib=rb-4.1.0&amp;q=15&amp;auto=format&amp;w=754&amp;h=503&amp;fit=crop&amp;dpr=3 2262w\" ><\/a>\n            <figcaption>\n              <span class=\"caption\"><em>Stachybotrys chartarum<\/em> mycotoxins have been blamed for lung issues after exposure to black mould.<\/span>\n              <span class=\"attribution\"><a class=\"source\" href=\"https:\/\/www.shutterstock.com\/image-illustration\/stachybotrys-chartarum-mould-toxic-common-fungi-1408495448\" target=\"_blank\" rel=\"noopener\">Kateryna Kon\/Shutterstock<\/a><\/span>\n            <\/figcaption>\n          <\/figure>\n\n<p>But just because inhaling spores is the probable route of contamination doesn\u2019t mean this is very likely.<\/p>\n\n<p>That\u2019s because <em>S. chartarum<\/em> doesn\u2019t release a lot of spores. Its spores are typically <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC145304\/\" target=\"_blank\" rel=\"noopener\">embedded in a slimy mass<\/a> and it rarely produces the <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC145304\/\" target=\"_blank\" rel=\"noopener\">spore densities needed to replicate the animal studies<\/a>.<\/p>\n\n<p>The original reports suggesting the US infants who were <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1566217\" target=\"_blank\" rel=\"noopener\">diagnosed with haemorrhagic lung disease<\/a> were exposed to toxic levels of mycotoxins <a href=\"https:\/\/www.cdc.gov\/mmwr\/preview\/mmwrhtml\/mm4909a3.htm\" target=\"_blank\" rel=\"noopener\">were also flawed<\/a>. <\/p>\n\n<p>Among other issues, the concentrations of <a href=\"https:\/\/www.cdc.gov\/mmwr\/preview\/mmwrhtml\/mm4909a3.htm\" target=\"_blank\" rel=\"noopener\">mould spores was calculated incorrectly<\/a>. Subsequent correction for these issues resulted in the association between <em>S. chartarum<\/em> and this disease cluster <a href=\"https:\/\/www.cdc.gov\/mold-health\/data-research\/facts-stats\/index.html\" target=\"_blank\" rel=\"noopener\">basically disappearing<\/a>. <\/p>\n\n<p>The <a href=\"https:\/\/www.aaaai.org\/\" target=\"_blank\" rel=\"noopener\">American Academy of Asthma Allergy and Immunology<\/a> states while there is a clear, well-established relationship between damp indoor spaces and detrimental health effects, there is no <a href=\"https:\/\/www.aaaai.org\/tools-for-the-public\/conditions-library\/allergies\/toxic-mold\" target=\"_blank\" rel=\"noopener\">good evidence black mould mycotoxins are involved<\/a>.<\/p>\n\n<h2 id=\"but-mould-can-cause-allergies\">But mould can cause allergies<\/h2>\n\n<p>Moulds can affect human health in ways unrelated to mycotoxins, typically through allergic reactions. Moulds including black moulds can trigger or worsen asthma attacks in people with <a href=\"http:\/\/doi.org\/10.1289\/ehp.1002410\" target=\"_blank\" rel=\"noopener\">mould allergies<\/a>. <\/p>\n\n<p>Some rarer but <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3114807\/\" target=\"_blank\" rel=\"noopener\">severe reactions can include allergic fungal sinusitis<\/a>, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK542329\/\" target=\"_blank\" rel=\"noopener\">allergic bronchopulmonary aspergillosis<\/a> and rarer still, <a href=\"https:\/\/www.lung.org\/lung-health-diseases\/lung-disease-lookup\/hypersensitivity-pneumonitis\" target=\"_blank\" rel=\"noopener\">hypersensitivity pneumonitis<\/a>. <\/p>\n\n<p>These can typically be <a href=\"https:\/\/www.hindawi.com\/journals\/ja\/2010\/510380\/\" target=\"_blank\" rel=\"noopener\">controlled by removing the mould<\/a> (or removing the person from the source of mould).<\/p>\n\n<p>People with impaired immune systems (such as people taking immune-suppressant medications) may also be <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3155160\/\" target=\"_blank\" rel=\"noopener\">prone to mould infections<\/a>.<\/p>\n\n<h2 id=\"in-a-nutshell\">In a nutshell<\/h2>\n\n<p>There is sufficient evidence that household mould is associated with respiratory issues attributable to their allergic effects. <\/p>\n\n<p>However, there is no strong evidence mycotoxins from household mould \u2013 and in particular black mould \u2013 are associated with substantial health issues.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img  loading=\"lazy\"  decoding=\"async\"  src=\"data:image\/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABAQMAAAAl21bKAAAAA1BMVEUAAP+KeNJXAAAAAXRSTlMAQObYZgAAAAlwSFlzAAAOxAAADsQBlSsOGwAAAApJREFUCNdjYAAAAAIAAeIhvDMAAAAASUVORK5CYII=\"  alt=\"The Conversation\"  width=\"1\"  height=\"1\"  style=\"border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important\"  referrerpolicy=\"no-referrer-when-downgrade\"  class=\" pk-lazyload\"  data-pk-sizes=\"auto\"  data-pk-src=\"https:\/\/counter.theconversation.com\/content\/258173\/count.gif?distributor=republish-lightbox-basic\" ><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https:\/\/theconversation.com\/republishing-guidelines --><\/p>\n\n  <p><span><a href=\"https:\/\/theconversation.com\/profiles\/ian-musgrave-1808\" target=\"_blank\" rel=\"noopener\">Ian Musgrave<\/a>, Senior lecturer in Pharmacology, <em><a href=\"https:\/\/theconversation.com\/institutions\/university-of-adelaide-1119\" target=\"_blank\" rel=\"noopener\">University of Adelaide<\/a><\/em><\/span><\/p>\n\n  <p>This article is republished from <a href=\"https:\/\/theconversation.com\" target=\"_blank\" rel=\"noopener\">The Conversation<\/a> under a Creative Commons license. Read the <a href=\"https:\/\/theconversation.com\/is-black-mould-really-as-bad-for-us-as-we-think-a-toxicologist-explains-258173\" target=\"_blank\" rel=\"noopener\">original article<\/a>.<\/p>\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"Peeradontax\/Shutterstock Ian Musgrave, University of Adelaide Mould in houses is unsightly and may cause unpleasant odours. More important&hellip;\n","protected":false},"author":1253,"featured_media":14982,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","fifu_image_url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/2\/26\/Mold_from_a_grapefruit.jpg","fifu_image_alt":"","footnotes":""},"categories":[12],"tags":[13054,13059,13073,13061,13057,13069,13052,13077,13078,13044,13053,13079,13060,13045,13064,13068,13058,13051,13046,13063,13070,13080,13076,13065,13055,13075,13041,13049,13071,13072,13066,13056,13074,13067,13047,13062,13050,13048,13043,13042],"class_list":{"0":"post-14980","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health-and-body","8":"tag-allergic-bronchopulmonary-aspergillosis","9":"tag-allergic-fungal-sinusitis-causes","10":"tag-allergy-vs-toxicity-mould","11":"tag-american-academy-mould-guidelines","12":"tag-asthma-triggered-by-mould","13":"tag-black-mould-and-lung-disease","14":"tag-black-mould-in-homes","15":"tag-damp-homes-respiratory-issues","16":"tag-damp-indoor-space-allergies","17":"tag-debunking-mould-health-myths","18":"tag-effects-of-mycotoxins-inhalation","19":"tag-fungal-infections-from-mould","20":"tag-fungal-spores-indoor-air","21":"tag-household-allergens-mould","22":"tag-household-fungi-allergic-reaction","23":"tag-household-mould-health-risks","24":"tag-immune-suppressed-mould-risks","25":"tag-immune-system-and-mould-infection","26":"tag-indoor-air-quality-mould","27":"tag-indoor-mould-respiratory-problems","28":"tag-misconceptions-about-black-mould","29":"tag-mould-allergy-symptoms","30":"tag-mould-and-asthma-link","31":"tag-mould-and-haemorrhagic-lung-disease","32":"tag-mould-and-hypersensitivity-pneumonitis","33":"tag-mould-exposure-in-children","34":"tag-mould-health-effects-children","35":"tag-mould-in-damp-buildings","36":"tag-mould-odour-and-health","37":"tag-mould-removal-for-health","38":"tag-mould-spore-inhalation-risks","39":"tag-mould-related-hypersensitivity","40":"tag-mycotoxins-from-mould","41":"tag-respiratory-illness-from-mould","42":"tag-roridin-toxin-effects","43":"tag-s-chartarum-health-concerns","44":"tag-satratoxins-health-effects","45":"tag-stachybotrys-chartarum-fungus","46":"tag-toxic-black-mould-myth","47":"tag-toxic-mould-science-facts","48":"cs-entry","49":"cs-video-wrap"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/modernsciences.org\/staging\/4414\/wp-json\/wp\/v2\/posts\/14980","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/modernsciences.org\/staging\/4414\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/modernsciences.org\/staging\/4414\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/modernsciences.org\/staging\/4414\/wp-json\/wp\/v2\/users\/1253"}],"replies":[{"embeddable":true,"href":"https:\/\/modernsciences.org\/staging\/4414\/wp-json\/wp\/v2\/comments?post=14980"}],"version-history":[{"count":1,"href":"https:\/\/modernsciences.org\/staging\/4414\/wp-json\/wp\/v2\/posts\/14980\/revisions"}],"predecessor-version":[{"id":14981,"href":"https:\/\/modernsciences.org\/staging\/4414\/wp-json\/wp\/v2\/posts\/14980\/revisions\/14981"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/modernsciences.org\/staging\/4414\/wp-json\/wp\/v2\/media\/14982"}],"wp:attachment":[{"href":"https:\/\/modernsciences.org\/staging\/4414\/wp-json\/wp\/v2\/media?parent=14980"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/modernsciences.org\/staging\/4414\/wp-json\/wp\/v2\/categories?post=14980"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/modernsciences.org\/staging\/4414\/wp-json\/wp\/v2\/tags?post=14980"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}